rs1267580705
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Von Hippel-Lindau Syndrome
0.010
GeneticVariation
BEFREE
About one third of VHL mutations are missense point mutations, with R167Q being the most common VHL point mutation in hereditary VHL disease.
24755468
2014
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
BEFREE
The authors observed evidence of interactions between PhIP and RCC susceptibility variants in 2 genes: inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2) (rs718314; multiplicative P for interaction = .03 and additive P for interaction =.002) and endothelial PAS domain-containing protein 1 (EPAS1) (rs7579899 ; additive P for interaction =.06).
26551148
2016
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
BEFREE
No significant association between rs7579899 or rs7105934 and RCC risk was observed.
22131124
2012
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
GWASCAT
Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC .
21131975
2011
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
GWASDB
Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC .
21131975
2011
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
BEFREE
Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC .
21131975
2011
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
GWASCAT
Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
28598434
2017
rs7579899
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.830
GeneticVariation
GWASCAT
Sex specific associations in genome wide association analysis of renal cell carcinoma.
31231134
2019
rs11894252
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.810
GeneticVariation
BEFREE
Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC .
21131975
2011
rs11894252
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.810
GeneticVariation
GWASCAT
Sex specific associations in genome wide association analysis of renal cell carcinoma.
31231134
2019
rs11894252
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.810
GeneticVariation
GWASDB
A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.
22010048
2012
rs11894252
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.810
GeneticVariation
GWASCAT
Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
28598434
2017
rs11894252
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.810
GeneticVariation
GWASDB
Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC .
21131975
2011
rs2121266
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.800
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs2121266
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
C
0.800
GeneticVariation
GWASCAT
Sex specific associations in genome wide association analysis of renal cell carcinoma.
31231134
2019
rs10211665
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs11125068
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs11684885
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs11689011
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs17034950
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs1867784
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs1867785
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs1867787
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs2034327
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011
rs2044456
×
Entrez Id:
2034
Gene Symbol:
EPAS1
EPAS1
Renal Cell Carcinoma
0.700
GeneticVariation
GWASDB
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
21131975
2011